/******* Do not edit this file *******
Simple Custom CSS and JS - by Silkypress.com
Saved: Sep 07 2024 | 01:05:14 */
/******* Do not edit this file *******
Simple Custom CSS and JS - by Silkypress.com
Saved: Jul 11 2023 | 15:25:23 */
/************/
/*  Colors  */
/************/
/******* Do not edit this file *******
Simple Custom CSS and JS - by Silkypress.com
Saved: Aug 22 2022 | 20:38:52 */
html, body {
  font-family: "Montserrat", sans-serif;
  font-family: "Montserrat", sans-serif !important;
}
h1 {
  font-size: clamp(24px, 2vw, 45px);
}
h2 {
  font-size: clamp(22px, 2vw, 36px);
  text-transform: uppercase;
}
h3 {
  font-size: clamp(20px, 2vw, 25px);
  text-transform: uppercase;
}
h4 {
  font-size: clamp(18px, 2vw, 22px);
}
h5 {
  font-size: clamp(16px, 2vw, 20px);
}
h6 {
  font-size: clamp(15px, 2vw, 18px);
}
p {
  font-size: clamp(14px, 2vw, 18px);
  line-height: 1.4;
  color: #2E2C2B;
}
li {
  font-size: clamp(14px, 2vw, 18px) !important;
  line-height: 1.4 !important;
}
::selection {
  color: #ffffff !important;
  background: #7E316F !important;
}
.text-light-section h2, .text-light-section h3 {
  color: #7E316F !important;
}
.text-dark-section h1, .text-dark-section p {
  color: #ffffff !important;
}
sup {
  font-size: smaller !important;
  line-height: 0;
}
.button-solid a {
  color: #ffffff !important;
  background-color: #7E316F !important;
  border: solid white 2px !important;
  border-radius: 20px !important;
  padding: 8px 16px !important;
  font-weight: 600 !important;
}
#disclaimer-container {
  display: flex !important;
  align-items: center !important;
}
.disclaimer-bar p {
  font-size: clamp(10px, 2vw, 16px) !important;
  line-height: 1.2 !important;
}
.sources-text p {
  font-size: clamp(10px, 2vw, 12px) !important;
  line-height: 1.1 !important;
}
.desktop-hidden {
  display: none;
}
#main {
  padding-top: 140px !important;
}
#header_meta {
  background-color: #7E316F !important;
  padding: 10px 10px;
}
#header_meta .sub_menu {
  top: 5px !important;
}
#header_meta .sub_menu ul li {
  border: none;
}
#header_meta .sub_menu ul li a {
  color: #ffffff !important;
  font-size: 16px;
  font-weight: 500;
}
#header_main {
  padding: 0 10px;
}
#header_main span.avia-menu-text {
  font-size: 16px;
  border-bottom: 2px solid transparent;
  transition: border-bottom 0.2s;
  padding-bottom: 6px !important;
}
#header_main span.avia-menu-text:hover {
  border-bottom: 2px solid #7E316F;
}
#header_main .avia-menu ul.av-main-nav li.mobile-nav-item {
  display: none;
}
#header_main .avia-menu li > a {
  padding: 0 0 0 15px !important;
}
#header span.logo {
  padding: 0.5% 0;
  max-height: 65px !important;
  width: 100%;
}
#main-header {
  position: relative;
}
#main-header .main-headline {
  color: white !important;
  padding: 50px 125px 50px 50px;
  border-top-right-radius: 500px;
  border-bottom-right-radius: 500px;
  position: relative;
  width: 45%;
  opacity: 0.9;
}
#main-header .main-headline:before {
  content: "";
  position: absolute;
  top: 0;
  left: 0;
  background: #7E316F;
  height: 100%;
  width: 100vw;
  visibility: visible;
  transform: translate3d(-99%, 0, 0);
  opacity: 1;
}
#main-header h1 {
  text-transform: none !important;
  font-weight: 500 !important;
  text-shadow: 4px 4px 2px rgba(0, 0, 0, 0.15);
  opacity: 1 !important;
}
#main-header .header-subtitle {
  font-size: clamp(18px, 1vw, 22px) !important;
  font-weight: 500;
  text-shadow: 4px 4px 2px rgba(0, 0, 0, 0.15);
  opacity: 1 !important;
}
#main-header .button-dark a {
  color: #ffffff;
  background-color: transparent !important;
  border: solid white 2px !important;
  border-radius: 20px;
  padding: 8px 16px;
  text-transform: uppercase;
  font-weight: 600;
}
#main-header .button-dark a:hover {
  color: #7E316F !important;
  background-color: #ffffff !important;
}
#main-header .button-solid a {
  color: #ffffff !important;
  background-color: #7E316F !important;
  border: solid white 2px !important;
  border-radius: 20px !important;
  padding: 8px 16px !important;
  font-weight: 600 !important;
}
#main-header .button-solid.sticky-button {
  position: fixed;
  top: 25vw;
  right: 1vw;
  transform: translate3d(120%, 0, 0);
  transition: 0.3s ease-out transform;
}
#main-header .button-solid.sticky-button.activate_show_button {
  transform: translate3d(0, 0, 0) !important;
}
#main-header .disclaimer-bar {
  position: absolute;
  bottom: 0;
  background-color: #2E2C2B;
  color: #ffffff;
  width: 100vw;
  left: 50%;
  transform: translate3d(-50vw, 0, 0);
  padding: 10px;
}
#main-header .scroll-down-link {
  bottom: 85px;
}
#about-palizade {
  padding: 2% 4%;
  background-size: auto;
  margin: auto;
}
#about-palizade .about-trial-content {
  padding: 5%;
}
#about-palizade .about-trial-content .about-trial-image img {
  max-width: 80% !important;
  height: auto;
}
#palizade-info {
  padding: 2% 4%;
}
#palizade-info .palizade-info-image img {
  max-width: 80% !important;
  height: auto;
  margin: auto;
}
#palizade-info .palizade-info-content {
  padding: 0 8% 0 2%;
}
#palizade-info .palizade-info-content .av_iconlist_title {
  padding-bottom: 15px !important;
}
#palizade-info .palizade-info-content .avia-icon-list-container {
  margin: 15px 0;
}
#palizade-info .av-iconlist-small li {
  padding-bottom: 15px !important;
}
#what-to-expect {
  padding: 2% 4%;
}
#what-to-expect .listed-content {
  font-size: clamp(14px, 2vw, 18px) !important;
  line-height: 1.4;
}
#what-to-expect .listed-content li {
  padding-bottom: 15px !important;
}
#what-to-expect .number-box-title {
  padding-top: 40px;
}
#what-to-expect .number-box-title p {
  font-weight: 600;
}
#what-to-expect .number-box {
  border: 2px solid #ffffff;
  border-radius: 0px 0px 0px 0px;
  padding: 20px 20px 20px 20px;
  width: 60%;
  margin: auto;
}
#what-to-expect .number-box .avia-no-number {
  opacity: 1;
  font-size: clamp(18px, 1vw, 28px) !important;
  font-weight: normal;
  letter-spacing: normal;
}
#what-to-expect .number-box .avia-single-number {
  opacity: 1;
  font-size: clamp(18px, 1vw, 28px) !important;
  font-weight: normal;
  letter-spacing: normal;
}
#what-to-expect .number-box .avia-animated-number-content {
  font-size: clamp(18px, 1vw, 28px) !important;
  border-top: 2px solid #ffffff !important;
  margin-top: 15px;
  padding-top: 15px;
}
#who-is-eligible {
  padding: 2% 4%;
}
#who-is-eligible .av-subheading {
  font-size: 18px;
  font-weight: 600;
}
#who-is-eligible .av_iconlist_title {
  padding-bottom: 15px !important;
}
#who-is-eligible .avia-icon-list-container {
  margin: 20px 20px;
}
#who-is-eligible .who-is-eligible-content {
  padding: 0 5%;
}
#who-is-eligible .who-is-eligible-image img {
  max-width: 80% !important;
  height: auto;
}
#study-locations {
  padding: 2% 5%;
}
#study-locations .container {
  padding: 0 50px !important;
}
#study-locations .map-spacer {
  width: 17% !important;
}
#study-locations .study-map-content .av-hotspot-container {
  background: #ffffff !important;
}
#study-locations .study-map-content .study-locations-subtext {
  padding-bottom: 20px;
}
#study-locations .study-locations-map-img {
  background: transparent !important;
}
#study-locations .study-locations-map-img .av-image-hotspot_inner {
  background: #7E316F;
  color: #7E316F !important;
  width: 65%;
  height: 65%;
}
#study-locations .study-locations-map-img .av-image-hotspot {
  height: 14px !important;
  width: 14px !important;
}
#study-locations .study-locations-map-img .av-image-hotspot-pulse {
  background: #7E316F;
  height: 25px !important;
  width: 25px !important;
  top: -8px;
  left: -8px;
}
.avia-tooltip p {
  font-size: 15px;
}
.avia-tooltip p span {
  display: block !important;
}
.av-hotspot-fallback-tooltip p {
  margin: 5px 0 !important;
}
#about-zetomipzomib {
  padding: 2% 4%;
}
#about-zetomipzomib h2 {
  text-align: center !important;
}
#about-zetomipzomib .about-zeto-main-content {
  text-align: center !important;
}
#about-zetomipzomib .av_textblock_section {
  max-width: 950px;
  margin: auto;
}
#about-lupus-nephritis {
  padding: 2% 6%;
}
#about-lupus-nephritis h2 {
  text-align: center !important;
}
#about-lupus-nephritis .about-lupus-main-content {
  text-align: center !important;
}
#about-lupus-nephritis .av_textblock_section {
  max-width: 1150px;
  margin: auto;
}
#about-lupus-nephritis ul.avia-icon-list li {
  padding: 6px !important;
  font-size: clamp(14px, 2vw, 16px) !important;
  line-height: 1.4;
}
#patient-accommodations {
  padding: 2% 4%;
}
#patient-accommodations .patient-accommodations-content {
  padding: 4%;
}
#patient-accommodations .patient-accommodations-image img {
  max-width: 80% !important;
  height: auto;
}
#resources {
  padding: 2% 8%;
}
#resources .av_textblock_section {
  max-width: 950px;
  margin: auto;
}
#resources .avia-content-slider-inner {
  max-width: 1400px;
  margin: auto;
}
#resources .slide-entry {
  width: calc(100%/4) !important;
}
#resources .slide-image {
  background: transparent !important;
}
#resources .slide-image .av-partner-fake-img {
  transition: all 0.2s ease-in-out;
}
#resources .slide-image .av-partner-fake-img:hover {
  transform: scale(1.1);
}
#faqs {
  padding: 2% 4%;
}
#faqs h3.av-special-heading-tag {
  font-weight: 500 !important;
}
#faqs p.toggler {
  padding-left: 70px !important;
  font-size: clamp(14px, 2vw, 18px) !important;
}
#faqs .toggle_icon {
  background: #7E316F !important;
  border: 10px solid #7E316F;
  margin-top: -10px;
  margin-left: 25px;
}
#faqs .toggle_icon .vert_icon {
  left: -1px;
  top: -5px;
  height: 11px;
}
#faqs .toggle_icon .hor_icon {
  top: -1px;
  left: -5px;
  width: 11px;
}
#faqs .toggler.activeTitle .toggle_icon {
  background: #ffffff !important;
}
#faqs .toggler.activeTitle .toggle_icon .vert_icon {
  color: #7E316F;
}
#faqs .toggler.activeTitle .toggle_icon .hor_icon {
  color: #7E316F;
}
#faqs p.toggler.activeTitle {
  background: #7E316F !important;
  color: #ffffff !important;
  border-bottom: 1px solid #7E316F !important;
  font-size: clamp(16px, 3vw, 18px);
}
#faqs ul li::marker {
  color: #7E316F;
}
#faqs ul li strong {
  color: #7E316F;
}
#faqs .toggle_content.invers-color {
  border: 2px solid #7E316F;
}
#contact {
  padding: 2% 4%;
}
#contact .desktop-hidden {
  display: none;
}
#contact .contact-content {
  width: auto !important;
  max-width: 50% !important;
  display: inline-block !important;
}
#contact hr {
  border: 1px solid #fff;
  margin: 30px 0 30px;
  width: 100%;
}
#contact h2.gform_title {
  display: none;
}
#contact p.gform_required_legend {
  display: none;
}
#contact label {
  font-weight: 400 !important;
}
#contact label span {
  color: #ffffff !important;
}
#contact input[type="text"], #contact input[type="email"], #contact textarea {
  border: 2px solid white !important;
  background-color: transparent !important;
  color: #ffffff !important;
}
#contact #gform_submit_button_1 {
  color: #ffffff;
  background-color: transparent !important;
  border: solid white 2px !important;
  border-radius: 20px;
  padding: 8px 30px;
  text-transform: uppercase;
  font-weight: 600;
}
#contact #gform_submit_button_1:hover {
  background-color: #ffffff !important;
  color: #7E316F !important;
}
#contact .av-content-full.alpha.units {
  padding-bottom: 0;
}
#contact .disclaimer-text-xs {
  padding-top: 3%;
}
#contact .gfield_required_asterisk {
  color: #fff !important;
}
#contact .gfield_label {
  font-size: 16px !important;
}
#socket .container {
  padding-top: 15px;
  padding-bottom: 15px;
  text-align: center;
}
#header #av-burger-menu-ul a:hover {
  background-color: #ffffff !important;
}
#header #av-burger-menu-ul li.av-active-burger-items {
  border-bottom: 1px solid #C6C6C6 !important;
  padding: 15px 0 !important;
}
@media only screen and (max-width: 1400px) {
  #header_meta {
    padding: 10px 0 !important;
  }
  #header_main {
    padding: 0 !important;
  }
  #patient-accomodations .patient-accomodations-content {
    padding: 0 !important;
  }
  .logo svg {
    max-width: 175px !important;
  }
  #header_main .avia-menu li > a {
    padding: 0 0 0 8px !important;
  }
}
@media only screen and (min-width: 1100px) and (max-width: 1200px) {
  #header_main span.avia-menu-text {
    font-size: 14px;
  }
  .av-main-nav > li > a {
    padding: 0 5px !important;
  }
  #header_meta .sub_menu ul li a {
    font-size: 12px;
  }
  .logo svg {
    max-width: 150px !important;
  }
}
@media only screen and (min-width: 990px) and (max-width: 1099px) {
  #header_main span.avia-menu-text {
    font-size: 13px;
  }
  .av-main-nav > li > a {
    padding: 0 5px !important;
  }
  #header_meta .sub_menu ul li a {
    font-size: 12px;
  }
  .logo svg {
    max-width: 135px !important;
  }
}
@media only screen and (max-width: 1200px) {
  #main-header .main-headline {
    width: 50% !important;
    padding: 50px 115px 50px 10px;
  }
  #what-to-expect .number-box {
    width: 75% !important;
    margin: 0 0 0 35px !important;
  }
}
@media only screen and (min-width: 990px) {
  #header-main span.logo {
    width: 100%;
  }
  #mobile-sticky-bar {
    display: none;
  }
}
@media only screen and (max-width: 989px) {
  .desktop-hidden {
    display: block;
  }
  .mobile-hidden {
    display: none;
    margin-top: 60px;
  }
  #header_meta {
    display: none;
  }
  #main-header .disclaimer-bar {
    padding: 0 4%;
  }
  #main-header .avia-menu ul.menu l1.mobile-nav-item {
    display: none !important;
  }
  #main-header .sticky-button {
    display: none !important;
  }
  #mobile-sticky-button {
    display: flex;
    justify-content: center;
    align-items: center;
  }
  #mobile-sticky-button .sticky-bar {
    position: sticky;
    bottom: 0;
  }
  #about-palizade .about-trial-image img {
    margin: auto;
    width: 80%;
  }
  #palizade-info .palizade-info-content {
    padding: 40px 0 0 0;
  }
  #palizade-info .palizade-info-content .listed-content {
    font-size: clamp(12px, 2vw, 18px);
    line-height: 1.4;
  }
  #what-to-expect .number-box-title {
    padding-top: 0;
  }
  #what-to-expect .number-box {
    width: 75% !important;
    margin: auto !important;
  }
  #what-to-expect .what-to-expect-content .listed-content {
    font-size: clamp(12px, 2vw, 18px);
    line-height: 1.4;
  }
  #what-to-expect .desktop-hidden {
    padding-top: 40px;
  }
  #who-is-eligible .who-is-eligible-image img {
    margin: auto;
    padding-bottom: 40px;
  }
  #who-is-eligible .who-is-eligible-content {
    padding: 0;
  }
  #who-is-eligible .who-is-eligible-content .listed-content {
    font-size: clamp(12px, 2vw, 18px);
    line-height: 1.4;
  }
  #study-locations .study-map-content {
    width: 100% !important;
  }
  #study-locations .study-map-content .av-hotspot-container {
    background: #ffffff !important;
  }
  #study-locations .study-map-content .av-image-hotspot-pulse {
    height: 34px !important;
    width: 34px !important;
    top: -10px !important;
    left: -10px !important;
  }
  #study-locations .study-map-content .av-hotspot-fallback-tooltip {
    background: transparent !important;
    padding: 10px 0 !important;
  }
  #study-locations .study-map-content .av-hotspot-fallback-tooltip .av-hotspot-fallback-tooltip-count {
    display: none;
  }
  #study-locations .study-map-content .av-hotspot-fallback-tooltip-inner {
    text-align: center !important;
    margin: 0 !important;
    border: 2px solid #ffffff !important;
    border-radius: 0 !important;
    padding: 10px !important;
  }
  #study-locations .study-map-locations-map-img .av-image-hotspot_inner {
    color: #7e316f !important;
  }
  #about-zetomipzomib {
    padding: 2% !important;
  }
  #about-lupus-nephritis {
    padding: 2% 4% !important;
  }
  #faqs .spacer-column {
    display: none;
  }
  #faqs .main-faqs-col {
    margin: auto !important;
    width: 100% !important;
  }
  #faqs .toggle_icon {
    margin-left: 5px !important;
  }
  #faqs p.toggler {
    padding-left: 55px !important;
  }
  #patient-accommodations .patient-accomodations-content {
    padding: 2% !important;
  }
  #patient-accommodations .patient-accommodations-image img {
    margin: auto !important;
  }
  #contact .desktop-hidden {
    display: block;
    margin-bottom: 50px;
  }
  #contact .mobile-hidden {
    display: none;
  }
  #contact .contact-content {
    max-width: 100% !important;
    text-align: center !important;
    margin-bottom: 50px !important;
  }
  #contact .flex_column_table {
    display: flex !important;
    flex-direction: column;
    align-items: center;
    margin-top: 0 !important;
  }
  #mobile-sticky-bar {
    position: fixed;
    bottom: 0;
    z-index: 2;
    min-height: 50px;
  }
  #mobile-sticky-bar .container {
    padding: 5px 0;
  }
  #mobile-headings, #disclaimer-container, #contact {
    position: relative;
  }
  #main-header, #mobile-headings, #contact, #disclaimer-container, #socket {
    z-index: 3 !important;
  }
  #study-locations .study-map-content .av-hotspot-fallback-tooltip {
    display: block !important;
  }
  #study-locations .study-map-content .av-hotspot-fallback-tooltip p {
    color: #fff !important;
  }
}
@media only screen and (max-width: 767px) {
  #main-header {
    margin-bottom: 100px !important;
  }
  #main-header .container.av-section-cont-open {
    width: 100% !important;
    max-width: 100% !important;
  }
  #main-header .main-headline {
    width: 100% !important;
    padding: 20px 20px 5px 20px !important;
    text-align: center !important;
    border-top-right-radius: 0;
    border-bottom-right-radius: 0;
  }
  #main-header h1 {
    font-size: 20px !important;
  }
  #main-header .scroll-down-link {
    display: none;
  }
  #main-header .text-dark-section {
    position: absolute;
    top: 0;
  }
  #mobile-headings {
    background: linear-gradient(to bottom, rgba(126, 49, 111, 0.8) 0, #7e316f 70%) !important;
    bottom: -100px;
    position: absolute;
  }
  #mobile-headings .text-dark-section {
    background: transparent !important;
  }
  #what-to-expect .number-box {
    width: 65% !important;
    margin: auto !important;
  }
  #about-zetomipzomib .about-zeto-content {
    text-align: left !important;
    padding: 0 !important;
    margin-bottom: 0 !important;
  }
  #about-lupus-nephritis .about-lupus-content {
    text-align: left !important;
    padding: 0 !important;
  }
  #resources .resource-logos .slide-entry-wrap {
    display: flex !important;
    flex-direction: column;
    align-items: center;
    justify-content: center;
  }
  #resources .resource-logos .slide-entry-wrap .slide-entry {
    margin: 15px 0 !important;
    width: 80% !important;
  }
  #resources .resource-logos .slide-entry-wrap .avia-logo-grid {
    margin-bottom: 15px !important;
  }
  #faqs .toggle_content p {
    font-size: clamp(14px, 2vw, 18px) !important;
    line-height: 1.4;
  }
  #faqs .toggle_content ul {
    margin: 4px 0;
  }
  #faqs .toggle_content ul li {
    font-size: clamp(14px, 2vw, 18px) !important;
    line-height: 1.4;
  }
  .responsive .logo svg {
    max-height: 45px !important;
  }
  .av-parallax .av-parallax-inner {
    background-position: 65% 100% !important;
  }
  #study-locations .container {
    padding: 0 !important;
  }
}
#socket .copyright {
  float: none !important;
  font-size: clamp(12px, 2vw, 16px);
}
@media only screen and (max-width: 600px) {
  #about-palizade .about-trial-image img {
    max-width: 100% !important;
  }
  #palizade-info .palizade-info-image img {
    max-width: 100% !important;
  }
  #who-is-eligible .who-is-eligible-image img {
    max-width: 100% !important;
  }
  #patient-accommodations .patient-accommodations-image img {
    max-width: 100% !important;
  }
}
@media only screen and (max-width: 484px) {
  #contact .break-text {
    display: block !important;
  }
}